Description
MethoxyPEGSuccinimidylCarboxymethylEsterforaminePEGylation,withsuperiorqualityspecificationof ≥95%Substitution.
JenKemTechnology’sMethoxyPEGSuccinimidylCarboxymethylEster (MethoxyPEGNHSorMethoxyPEGSCM)isahighqualityaminereactivePEGproductwithastablenon-degradablelinkerbetweenthePEGpolymericchainandtheNHSester.MethoxyPEGSuccinimidylCarboxymethylEsterreactswiththeaminegroupoflysine(s)atroomtemperatureinlessthan1hratpH7-8.Shorter hydrolysishalflifeofM-PEG-SCMensuresmaximumselectivitytowardsmoststericallyavailableaminegroups.
JenKemTechnologyoffersMethoxyPEGSCMEster withMW2kDa (M-SCM-2000),MW3kDa(M-SCM-3000),MW5kDa(M-SCM-5000),MW10kDa(M-SCM-10K),MW20kDa(M-SCM-20K),MW30kDa(M-SCM-30K),MW35kDa(M-SCM-35K)andMW40kDa(M-SCM-40K),in1gand10gpackingsizes. DifferentMWofMethoxyPEGSCM Esterproductsmaybeavailablebycustomsynthesis,pleaseemailus attech@jenkemusa.comfordetailsoncustomPEGs.OtherlinearNHSestersareavailable–pleaseselectother stablelinkerNHSPEGs,or cleavablelinkerNHSPEGs.JenKemTechnology providesrepackagingservicesforanadditionalfee,pleasecontactusifyourequireadifferentpackagesizethanourcatalogselection.
BulkPEGsandGMPgradePEGsaremade-to-order.Pleasecontactus forbulkpricing.
ClickheretodownloadtheMSDS
References:
- Bisso,S.,etal.,DualdeliveryofnucleicacidsandPEGylated-bisphosphonatesviacalciumphosphatenanoparticles,EuropeanJournalofPharmaceuticsandBiopharmaceutics,2019.
- Moussa,A.,etal.,Reducing-end“clickable”functionalizationsofchitosanoligomersforthesynthesisofchitosan-baseddIBLockcopolymers,CarbohydratePolymers,2019,V.219,P.387-394.
- Rajkumar,S.,etal.,Multi-functionalcore-shellFe3O4@Aunanoparticlesforcancerdiagnosisandtherapy,ColloidsandSurfacesB:Biointerfaces,2019,V.174,P.252-259.
- Rompicharla,S.V.,etal.,BiotinfunctionalizedPEGylatedpoly(amidoamine)dendrimerconjugateforactivetargetingofpaclitaxelincancer,Internationaljournalofpharmaceutics,2019,557:329-41.
- Feng,J.,etal.,DendriticPolylysineBasedανβ3IntegrinTargetedProbeforNear-infraredFluorescentImagingofGlioma,ColloidsandSurfacesB:Biointerfaces,2019.
- Han,S.,etal.,Anovelsynergetictargetingstrategyforgliomatherapyemployingborneolcombinationwithangiopep-2-modified,DOX-loadedPAMAMdendrimer,Journalofdrugtargeting,2018,26(1),pp.86-94.
- Hu,Q.,etal.,ChondrocyteaffinitypeptidemodifiedPAMAMconjugateasananoplatformfortargetingandretentionincartilage,Nanomedicine,2018,13(7),pp.749-767.
- Li,H.,etal.,Dendron‐GraftedPolylysine‐BasedDual‐ModalNanoprobeforUltra‐EarlyDiagnosisofPancreaticPrecancerosisviaTargetingaUrokinase‐TypePlasminogenActivatorReceptor,Advancedhealthcarematerials,2018,7(5),p.1700912.
- Zhang,L.,etal.,InvivotumoractivecancertargetingandCT-fluorescencedual-modalimagingwithnanoprobebasedongoldnanorodsandInP/ZnSquantumdots,JournalofMaterialsChemistryB,2018.
- Badkas,A.,etal.,ModulationofinvitrophagocyticuptakeandimmunogenicitypotentialofmodifiedHerceptin®-conjugatedPLGA-PEGnanoparticlesfordrugdelivery,ColloidsandSurfacesB:Biointerfaces,2018,V.162,P.271-278.
- Rajkumar,S.,etal.,Multi-functionalnanocarriersbasedonironoxidenanoparticlesconjugatedwithdoxorubicin,poly(ethyleneglycol)andfolicacidastheranosticsforcancertherapy,ColloidsandSurfacesB:Biointerfaces,2018,V.170,P.529-537.
- Pan,H.M.,etal.,EngineeringandDesignofPolymericShells:InwardsInterweavingPolymersasMultilayerNanofilm,ImmobilizationMatrixorChromatographyResins.ACSAppliedMaterials&Interfaces,2017.
- Liu,C.,etal.,iRGD-mediatedcore-shellnanoparticlesloADIngcarmustineandO6-benzylguanineforgliomatherapy,JournalofDrugTargeting,2017,25(3):235-46.
- Gao,W.,etal.,Transferrinreceptor-targetedpH-sensitivemicellarsystemfordiminutionofdrugresistanceandtargetabledeliveryinmultidrug-resistantbreastcancer,InternationalJournalofNanomedicine,2017,12:1047.
- Yang,C.,etal.,EffectsofPEGylationonbiomimeticsynthesisofmagnetoferritinnanoparticles,JournalofNanoparticleResearch,2017,19(3):101.
- Jiang,G.,etal.,Formulationoftemozolomide-loadednanoparticlesandtheirtargetingpotentialtomelanomacells,Oncologyreports,2017,37(2):995-1001.
- Han,S.,etal.,ANovelSynergeticTargetingStrategyforGliomaTherapyEmployingBorneolCombinationwithAngiopep-2-modified,DOX-loadedPAMAMDendrimer,JournalofDrugTargeting,2017,1-20.
- Xu,L.,etal.,Oxidizedcatechol-derivedpoly(ethyleneglycol)forthiol-specificconjugation.ReactiveandFunctionalPolymers,2017.
- Yu,Y.,etal.,AnewNIR-triggeredDOXandICGco-deliverysystemforenhancedmultidrugresistantcancertreatmentthroughsimultaneouschemo/photothermal/photodynamictherapy,ActaBiomaterialia,2017.
- Ye,J.,etal.,High-YieldSynthesisofMonomericLMWP(CPP)-siRNACovalentConjugateforEffectiveCytosolicDeliveryofsiRNA,Theranostics,2017,7(9),2495-2508
- Yuan,Z.,etal.,Multifunctionalnanoparticlesco-deliveringEZH2siRNAandetoposideforsynergistictherapyoforthotopicnon-small-celllungtumor,JournalofControlledRelease,2017,v.268,P.198-211.
- Alejo-Gonzalez,K.,etal.,PEGylationofcytochromeP450enhancesitsbiocatalyticperformanceforpesticidetransformation,InternationalJournalofBIOLOGicalMacromolecules,2017,v.105:1,P.163-170.
- Henley,W.H.,etal.,Highresolutionseparationsofchargevariantsanddisulfideisomersofmonoclonalantibodiesandantibodydrugconjugatesusingultra-highvoltagecapillaryelectrophoresiswithhighelectricfieldstrength,JournalofChromatographyA,2017,V.1523,P.72-79.
- Yu,Y.,etal.,AnewNIR-triggereddoxorubicinandphotosensitizerindocyaninegreenco-deliverysystemforenhancedmultidrugresistantcancertreatmentthroughsimultaneouschemo/photothermal/photodynamictherapy,ActaBiomaterialia,2017,V.59,P.170-180.
- Cao,X.,etal.,ModulatingtheCellularImmuneResponseofOligonucleotidesbyBrushPolymer‐AssistedCompaction,Small,2017,13(43).
- Xu,Z.,etal.,Apoly(amidoamine)dendrimer-basednanocarrierconjugatedwithAngiopep-2fordual-targetingfunctionintreatinggliomacells, Polym.Chem.,2016,7,715-721.
- Dasargyri,A.,etal.,FindingsquestioningtheinvolvementofSigma-1receptorintheuptakeofanisamide-decoratedparticles,JournalofControlledRelease,2016.
- Son,Y.J.,etal.,ElectrospunNanofibrousSheetsforSelectiveCellCapturinginContinuousFlowinMicrochannels, Biomacromolecules,2016.
- Kumar,A.T.,etal., Substrate-basednear-infraredimagingsensorsenablefluorescencelifetimecontrastviabuilt-indynamicfluorescencequenchingelements.ACSSensors,2016.
- Wang,W.,etal.,Doxorubicin-loadedpH-sensitivepolymericblendsforsynergisticcancertreatment, RSCAdv.,2016,6,31167-31176.
- Zhou,F.,etal.,TargeteddeliveryofmicroRNA-126tovascularendothelialcellsviaREDVpeptidemodifiedPEG-trimethylchitosan.Biomaterialsscience,2016,4(5):849-56.
- Li,F.,etal.,Non-invasivelydifferentiatingextentofliverfibrosisbyvisualizinghepaticintegrinαvβ3expressionwithanMRImodalityinmice,Biomaterials,2016,102:162-74.
- Gao,X.,etal.,NanoagoNIST-mediatedendothelialtightjunctionopening:Astrategyforsafelyincreasingbraindrugdeliveryinmice,JournalofCerebralBloodFlow&Metabolism,2016.
- Wu,D.,etal.,Phenylboronicacid-functionalizedpolyamidoamine-mediatedBcl-2siRNAdeliveryforinhibitingthecellproliferation,ColloidsandSurfacesB:Biointerfaces,2016,146:318-25.
- Rasson,A.S.,etal.,FilamentAssemblybySpire:KeyResiduesandConcertedActinBinding,JournalofMolecularBiology,2015,427 (4), p:824-839.
- Jiao,Y.,etal.,FunctionalizedHollowMesoporousSilicaNanoparticles‐BasedControlledDual‐DrugDeliverySystemforImprovedTumorCellCytotoxicity,Particle&ParticleSystemsCharacterization,2015,32(2):222-233.
- OztugDurer,Z.A.,etal.,MetavinculinTunestheFlexibilityandtheArchitectureofVinculin-InducedBundlesofActinFilaments,JournalofMolecularBiology,2015,427:17,P.2782-2798.
- Schmid,E.M.,etal.,Chapter17–Reconstitutionofproteinsonelectroformedgiantunilamellarvesicles,In:MethodsinCellBiology,AcademicPress,2015,128,P.319-338.
- Morry,J.,etal.,DermaldeliveryofHSP47siRNAwithNOX4-modulatingmesoporoussilica-basednanoparticlesfortreatingfibrosis,Biomaterials,2015,66.
- Fu,H.,etal.,Tumor‐TargetedPaclitaxelDeliveryandEnhancedPenetrationUsingTAT‐DecoratedliposomesComprisingRedox‐ResponsivePoly(EthyleneGlycol),JournalofPharmaceuticalScience,2015,104(3),1160-1173.
- McLeod,V.M.,etal.,OptimalPEGylationcanImprovetheExposureofInterferonintheLungsFollowingPulmonaryAdministration,JournalofPharmaceuticalSciences,2015,104(4),1421-1430.
- Cheng,L.,etal.,ConstructionandevaluationofPAMAM–DOXconjugateswithsuperiortumorrecognitionandintracellularacid-triggereddrugreleaseproperties,ColloidsandSurfacesB:Biointerfaces,2015,136,P.37-45.
- Zheng,S.,etal.,SalvagingbrainischemiabyincreasingneuroprotectantuptakeviananoagonistmediatedbloodbrainbarrierpermeABIlityenhancement,Biomaterials,2015,66,P.9-20.
- Paez,J.I.,etal.,GaugingandTuningCross-LinkingKineticsofCatechol-PEGAdhesivesviaCatecholamineFunctionalization, Biomacromolecules,2015,16(12),3811-3818.
- Senanayake, T.H.,etal.,Nanogel-ConjugatedReverseTranscriptaseInhibitorsandTheirCombinationsasNovelAntiviralAgentswithIncreasedEfficacyagainstHIV-1Infection, MolecularPharmaceutics,2015,12(12),4226
- Yu,H.,etal.,Enzymesensitive,surfaceengineerednanoparticlesforenhanceddeliveryofcamptothecin,JournalofControlledRelease,2015,216,P.111-120.
- Zirbs,R.,etal.,Melt-graftingforthesynthesisofcore–shellnanoparticleswithultra-highdispersantdensity, Nanoscale,2015,7,11216-11225.
- Chan,L.J.,etal.,PEGylationDoesNotSignificantlyChangetheInitialIntravenousorSubcutaneousPharmacokineticsorLymphaticExposureofTrastuzumabinRatsbutIncreasesPlasmaClearanceafterSubcutaneousAdministration, MolecularPharmaceutics,2015,12(3),794-809.
- Crouzier,T.,etal., ModulatingMucinHydrationandLubricationbyDeglycosylationandPolyethyleneGlycolBinding.Adv.Mater.Interfaces,2015,2.
- Wang,K.,etal.,DevelopmentofbiodegradablepolymericimplantsofRGD-modifiedPEG-PAMAM-DOXconjugatesforlong-termintratumoralrelease, DrugDelivery, 2015,22:3.
- Nannan,L.,etal.,Antitumorandantimetastaticeffectsofpemetrexed-loadedtargetednanoparticlesinB16bearingmice,Drugdelivery,2015,1-9.
- FahrländerE.,etal.,PEGylatedhumanserumalbumin(HSA)nanoparticles:preparation,characterizationandquantificationofthePEGylationextent,Nanotechnology,2015,26(14),145103.
- Zhao,G.,etal.,FunctionalPEG–PAMAM-TetraphosphonateCappedNaLnF4NanoparticlesandtheirColloidalStabilityinPhosphateBuffer.Langmuir,2014,30(23):p.6980-6989.
- Petek,N.A.andR.D.Mullins,ChapterTwo–BacterialActin-LikeProteins:PurificationandCharacterizationofSelf-AssemblyProperties,inMethodsinEnzymology,D.V.Ronald,Editor.,2014,p.19-34.
- Hu,W.,etal., RedoxandpH-responsivepoly(amidoamine)dendrimer-poly(ethyleneglycol)conjugateswithdisulfidelinkagesforefficientintracellulardrugrelease, ColloidsSurfBBiointerfaces,2014,123,p:254-63.
- Liu,S.,etal., NIRinitiatedandpHsensitivesingle-wallcarbonnanotubesfordoxorubicinintracellulardelivery, J.Mater.Chem.B,2014,2, 1125.
- Gonzalez,A.L.,etal.,Integrin-drivenmonocytetodendriticcellconversioninmodifiedextracorporealphotochemotherapy,ClinExpImmunol,2014,175(3):449-457.
- Chen,J.,etal.,AFacileStrategyforInSituControlledDeliveryofDoxorubicinwithapH-SensitiveInjectableHydrogel,NanoLIFE,2014,04:03.
- Wang,K.,etal.,Tumorpenetrabilityandanti-angiogenesisusingiRGD-mediateddeliveryofdoxorubicin-polymerconjugates,Biomaterials,2014,35:30, p.8735-8747.
- Qin,L.,etal.,Adual‑targetingliposomeconjugatedwithtransferrinandarginine‑glycine‑asparticacidpeptideforglioma‑targetingtherapy,OncologyLetters,2014,8,2000-2006.
- Yuan,W.,etal.,IncreasedDeliveryofDoxorubicinIntoTumorCellsUsingExtracellularlyActivatedTATFunctionalizedLiposomes:InVitroandInVivoStudy,JournalofBiomedicalNanotechnology,2014,10:8,p.1563-1573(11).
- Zhou.J.,etal., Enhancedandselectivedeliveryofenzymetherapyto9L-gliomatumorviamagnetictargetingofPEG-modified,β-glucosidase-conjugatedironoxidenanoparticles,InternationalJournalofNanomedicine,2014,9:2905-2917.
- Saville,S.L.,etal.,Theformationoflinearaggregatesinmagnetichyperthermia:Implicationsonspecificabsorptionrateandmagneticanisotropy,JournalofColloidandInterfaceScience, 2014,424,P.141-151.
- Kong,X.,etal.,Anovelmultifunctionalpoly(amidoamine)dendrimericdeliverysystemwithsuperiorencapsulationcapacityfortargeteddeliveryofthechemotherapydrug10-hydroxycamptothecin.InternationalJournalofPharmaceutics,2014,465(1–2),p.378-387.
- Si,Z.,etal.,pH-responsivenear-infrarednanoprobeimagingmetastasesbysensingacidicmicroenvironment, RSCAdv.,2014,4,55548-55555.
- Mei,L.,etal.,IncreasedtumortargeteddeliveryusingamultistageliposomesystemfunctionalizedwithRGD,TATandcleavablePEG.InternationalJournalofPharmaceutics,2014,468(1–2),p.26-38.
- Tang,J.,etal.,Liposomesco-modifiedwithcholesterolanchoredcleavablePEGandoctaargininesfortumortargeteddrugdelivery, JournalofDrugTargeting, 2014,22:4.
- Zheng,S.,etal.,MultimodalNanoprobesEvaluatingPhysiologicalPoreSizeofBrainVasculaturesinIschemicStrokeModels.AdvancedHealthcareMaterials,2014,3:1909–1918.
- Gao,X.,etal., Overcomingtheblood–brainbarrierfordeliveringdrugsintothebrainbyusingadenosinereceptornanoagonist.ACSnano,2014,8(4):3678-89.
- Wang,Q.,etal.,Comparativestudiesofsalinomycin-loadednanoparticlespreparedbynanoprecipitationandsingleemulsionmethod, NanoscaleResearchLetters, 2014,9:351.
- HaiouQu,etal., ControllableinSitu SynthesisofMagnetiteCoatedSilica-CoreWater-DispersibleHybridNanomaterials,Langmuir,2013,29(33) p:10573–10578.
- Malik,R.,etal., Asingle-layerpeptidenanofiberforenhancingthecytotoxicityoftrastuzumab(anti-HER), JournalofNanoparticleResearch, 2013,15:1682.
- Giger,E.V.,etal.,siRNAtransfectionwithcalciumphosphatenanoparticlesstabilizedwithPEGylatedchelators,AdvHealthcMater,2013,2(1):134-144.
- Hansen,S.D,etal., Cytoplasmicactin:purificationandsinglemoleculeassemblyassays,InAdhesionProteinProtocols,2013,p.145-170.
- Gao,X.,etal.,Up-regulatingbloodbrainbarrierpermeabilityofnanoparticlesviamultivalenteffect,Pharmaceuticalresearch,2013,30.10:2538-2548.
- Lei,Y.,etal. Glutathione-sensitiveRGD-poly(ethyleneglycol)-SS-polyethylenimineforintracranialglioblastomatargetedgenedelivery.J.GeneMed.,2013,15:291–305.
- Sabar,M.F.,etal.,SynthesisandBioactivityStudyof30KDaLinearPEG-InterferonanditsComparisonwithTri-BranchedPEG-Interferon.J.Chem.Soc.,2013,35.1:119.
- Ran,R.,etal.,Enhancedtumoraccumulationandcellularuptakeofliposomesmodifiedwithether-bondlinkedcholesterolderivatives,DiePharmazie-AnInternationalJournalofPharmaceuticalSciences,2013,68.8:668-674.
- Scott,M.A., Ultra-rapid2-Dand3-Dlasermicroprintingofproteins.Diss.MassachusettsInstituteofTechnology,2013.
- Sun,C.,etal.,BifunctionalPEGylatedexenatide-amylinomimetichybridstotreatmetabolicdisorders:anexampleoflong-actingdualhormonaltherapeutics,Journalofmedicinalchemistry,2013,56.22:9328-9341.
- Li,R.,etal.,IntelligentlyTargetedDrugDeliveryandEnhancedAntitumorEffectbyGelatinase-ResponsiveNanoparticles.PLoSONE,2013,8(7):e69643.
- Keefe,A.J.,etal.,Poly(zwitterionic)proteinconjugatesofferincreasedstabilitywithoutsacrificingbindingaffinityorbioactivity, NatureChemistry,2012,4,p:59–63.
- Lee,G.,etal., Real-TimeQuantitativeMonitoringofSpecificPeptideCleavagebyaProteinaseforCancerDiagnosis, Angew.Chem.Int.Ed.,2012,51,5837–5841.
- Huang,G.,etal., DextranbasedpH-sensitivenear-infrarednanoprobeforinvivodifferential-absorptiondual-wavelengthphotoacousticimagingoftumors, J.Mater.Chem.,2012,22,22575.
- Doronin,K.,etal.,ConstructionofTargetedandArmedOncolyticAdenoviruses,MethodsinMolecularBiology,OncolyticViruses,2012,797.
- Qin,L.,etal.,Gelatinase-stimulistrategyenhancesthetumordeliveryandtherapeuticefficacyofdocetaxel-loadedpoly(ethyleneglycol)-poly(varepsilon-caprolactone)nanoparticles,IntJNanomedicine7,2012,281-295.
- Gillich,T.,etal.,Self-AssemblyofFocalPointOligo-catecholEthyleneGlycolDendronsonTitaniumOxideSurfaces:AdsorptionKinetics,SurfaceCharacterization,andNonfoulingProperties,J.A.C.S.,2011,133(28), p:10940–10950.
- Wang,Y.Y.,etal.,IntroducingRGDPeptidesonPHBVFilmsthroughPEG-ContainingCross-LinkerstoImprovetheBiocompatibility,Biomacromolecules,2011,12(3), p:551–559.
- Soontornworajit,B.,etal.,Affinityhydrogelsforcontrolledproteinreleaseusingnucleicacidaptamersandcomplementaryoligonucleotides,Biomaterials,2011,32(28):6839-6849.
- Zhang,L.,etal.,RGD-modifiedPEG–PAMAM–DOXconjugates:Invitroandinvivostudiesforglioma,EuropeanJournalofPharmaceuticsandBiopharmaceutics,2011,79:2,P.232-240.
- Lu,Z-X,etal., DevelopmentofsmallinterferingRNAdeliverysystemusingPEI-PEG-APRPGpolymerforantiangiogenicvascularendothelialgrowthfactortumor-targetedtherapy,InternationalJournalofNanomedicine,2011,6:1661-1673.
- Kuai,R.,etal.,TargetedDeliveryofCargoesintoaMurineSolidTumorbyaCell-PenetratingPeptideandCleavablePoly(ethyleneglycol)ComodifiedLiposomalDeliverySystemviaSystemicAdministration,Mol.Pharmaceutics,2011,8(6),p:2151–2161.
- Chen,H.,etal.,High-levelproductionofuricasecontainingketofunctionalgroupsforsite-specificPEGylation,BiochemicalEngineeringJournal,2011,58–59,p.25-32.
- Zhu,S.,etal.,PEGylatedPAMAMDendrimer-DoxorubicinConjugates:InVitroEvaluationandInVivoTumorAccumulation,PharmaceuticalResearch, 2010,27:1,p.161-174.
- Georgianna,W.E.,etal.,PhotocleavablePolyethyleneGlycolfortheLight-RegulationofProteinFunction,BioconjugateChem.,2010,21(8) p:1404–1407.
- Zhu,S.,etal., PartlyPEGylatedpolyamidoaminedendrimerfortumor-selectivetargetingofdoxorubicin:theeffectsofPEGylationdegreeanddrugconjugationstyle,Biomaterials,2010,31(6):1360-71.
- Huang,R.,etal.,EvaluationandmechanismstudiesofPEGylateddendrigraftpoly-L-lysinesasnovelgenedeliveryvectors,Nanotechnology,2010,21:26.
- Kuai,R.,etal.,EfficientDeliveryofPayloadintoTumorCellsinaControlledMannerbyTATandThiolyticCleavablePEGCo-ModifiedLiposomes, MolecularPharmaceutics,2010,7(5),1816-1826.
- Liu,Q.,etal.,TargeteddeliveryofmiR-200c/DOCtoinhibitcancerstemcellsandcancercellsbythegelatinases-stimulinanoparticles,Biomaterials,2013,34:29,p.7191-7203.
- Zhang,H.,etal.,EfficientTransfectionofBlood−BrainBarrierEndothelialCellsbyLipoplexesandPolyplexesinthePresenceofNuclearTargetingNLS-PEG-AcridineConjugates,BioconjugateChemistry,2009,20(1),120-128.
- Doronin,K.,etal.,ChemicalModificationwithHighMolecularWeightPolyethyleneGlycolReducesTransductionofHepatocytesandIncreasesEfficacyofIntravenouslyDeliveredOncolyticAdenovirus,HumanGeneTherapy,2009,20(9):975-988.
- Zhang,H.,etal.,EfficientNuclearTargetingbyNLS-PEG-AcridineConjugatesintheTransfectionofBlood-BrainBarrierEndothelialCellswithLipoplexesandPolyplexes,Bioconjugatechemistry,2009,20(1):120-128.
- Cao,J.,etal.,Quantitativedeterminationofpegylatedconsensusinterferoninrhesusmonkeyserumusingacompetitiveenzyme-linkedimmunosorbentassay, ImmunopharmacologyandImmunotoxicology, 2009,31:4.
- Ochs,C.J.,etal.,Low-Fouling,Biofunctionalized,andBiodegradableClickCapsules,Biomacromolecules,2008,9(12),p:3389–3396.
- Weaver,E.A.,etal.,EffectsofShieldingAdenoviralVectorswithPolyethyleneGlycolonVector-SpecificandVaccine-MediatedImmuneResponses,HumanGeneTherapy,2008,19:1369–1382.
- Hofherr,S.E.,etal., ModificationofAdenoviralVectorsWithPolyethyleneGlycolModulatesInVivoTissueTropismandGeneExpression,MolecularTherapy,2008,167.
Foundedin2001byexpertsinPEGsynthesisandPEGylation,JenKemTechnologyspecializesexclusivelyinthedevelopmentandmanufacturingofhighqualitypolyethyleneglycol(PEG)productsandderivatives,andrelatedcustomsynthesisandPEGylationservices.JenKemTechnologyisISO9001andISO13485certified,andadherestoICHQ7AguidelinesforGMPmanufacture.TheproductionofJenKem®PEGsisback-integratedtoin-housepolymerizationdirectlyfromethyleneoxide,enablingfaciletraceabilityforregulatedcustomers.JenKemTechnologycaterstothePEGylationneedsofthepharmaceutical,biotechnology,medicaldeviceanddiagnostics,andemergingchemicalspecialtymarkets,fromlaboratoryscalethroughlargecommercialscale.