Description
GlucosePEGSuccinimidylCarboxymethylEsterwithsuperiorqualityspecificationof ≥90%Substitution.
JenKemTechnology’sGlucosePEGSuccinimidylCarboxymethylEsterisahighqualityaminereactivePEGproductwithasuccinimidylcarboxymethylesteractivegroupandatargetingglucosegroup.Glucose PEG SuccinimidylCarboxymethylEster reactswithaminegroupoflysine(s)atroomtemperatureinlessthan1hr,atpH7-8.Thepresenceofthemonosaccharidesugargroup(Glucose)increasessignificantlytheselectivityofthePEGylationreaction.
JenKemTechnologyoffersGlucose PEGSuccinimidylCarboxymethylEsterwithMW35000(GLUC-SCM-35K),in1gand10gpackingsizes.DifferentMWofGlucose PEGSuccinimidylCarboxymethylEsterproductsmaybeavailablebycustomsynthesis,pleaseemailus attech@jenkemusa.comfordetailsoncustomPEGs. JenKemTechnology providesrepackagingservicesforanadditionalfee,pleasecontactusifyourequireadifferentpackagesizethanourcatalogselection.
BulkPEGsandGMPgradePEGsaremade-to-order.Pleasecontactusforbulkpricing.
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References:
1. He,H.,etal.,Developmentofmannosefunctionalizeddendrimericnanoparticlesfortargeteddeliverytomacrophages:useofthisplatformtomodulateatherosclerosis,TranslationalResearch,2018,Vol.193,P.13-30.
2.Drappier,C., pH-ResponsiveSurfaceShieldingByElectrostaticAdsorptionofPEGSegmentsWithAnionicChainEnd, UniversiteBordeaux,2013.
3. Weaver,E.A.,etal., EffectsofShieldingAdenoviralVectorswithPolyethyleneGlycolonVector-SpecificandVaccine-MediatedImmuneResponses, HumanGeneTherapy2008,19:1369–1382.
Note:StartingJuly2016,GlucosePEGSuccinimidylCarboxymethylEsteristhenewnameoftheproduct GlucosePEGNHS(MW35000(GLUC-NHS-35K)
Foundedin2001byexpertsinPEGsynthesisandPEGylation,JenKemTechnologyspecializesexclusivelyinthedevelopmentandmanufacturingofhighqualitypolyethyleneglycol(PEG)productsandderivatives,andrelatedcustomsynthesisandPEGylationservices.JenKemTechnologyisISO9001andISO13485certified,andadherestoICHQ7AguidelinesforGMPmanufacture.TheproductionofJenKem®PEGsisback-integratedtoin-housepolymerizationdirectlyfromethyleneoxide,enablingfaciletraceABIlityforregulatedcustomers.JenKemTechnologycaterstothePEGylationneedsofthepharmaceutical,biotechnology,medicaldeviceanddiagnostics,andemergingchemicalspecialtymarkets,fromlaboratoryscalethroughlargecommercialscale.
